Respiratory depression after epidural and intrathecal narcotics
نویسندگان
چکیده
منابع مشابه
Intrathecal and epidural narcotics.
This paper presents an overall review of epidural and intrathecal narcotics. The early laboratory studies and initial clinical applications are presented. This is followed by a description of the mechanism of action of narcotics acting both intrathecally and epidurally, and some of the similarities and differences between narcotics and local anesthetic drugs. Technique, dosages, indications, an...
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BACKGROUND Perispinal anaesthesia for Caesarean section allows injection of epidural (ED) or intrathecal (i.t.) morphine to provide long-lasting postoperative analgesia. To compare these two routes, a prospective, randomized, double-blinded study of 53 patients undergoing elective Caesarean section was performed. METHODS Combined spinal-epidural anaesthesia with 6 mg of i.t. hyperbaric bupiva...
متن کاملRespiratory depression following combination of epidural buprenorphine and intramuscular ketorolac.
A 48-year-old man who had undergone thoracotomy for carcinoma of the middle third of his oesophagus developed severe postoperative respiratory depression following intramuscular ketorolac 30 mg 2 h after 150 micrograms epidural buprenorphine. Summation of analgesia by drugs used in combination can have deleterious respiratory effects.
متن کاملEpidural, intrathecal pharmacokinetics, and intrathecal bioavailability of ropivacaine.
BACKGROUND Ropivacaine is used by the epidural route for postoperative pain management with various neuraxial techniques. Given the widespread use of these techniques and the relative paucity of data on spinal disposition of local anesthetics, we evaluated through an experimental animal model, the spinal disposition of ropivacaine, allowing further studies of factors influencing their intrathec...
متن کاملEarly respiratory depression during caesarean section following epidural meperidine.
A case of respiratory depression which occurred following administration of epidural meperidine during Caesarean section is described. Epidural meperidine, 75 mg (10 mg.ml-1) was given after delivery of the infant to provide postoperative analgesia. Oxygen desaturation (SaO2 90%) and a decrease in respiratory rate (4.min-1) were noted 30 min after epidural meperidine was administered. Naloxone,...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1982
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1982.tb01245.x